Is everyone getting the error with 80080005 in it? Searching the web this always seems to be trying to attach to something that running under different user credentials. For example, if I start iTunes normally, I can attach just fine. But if I start iTunes as administrator, then try to attach I get this error. So somehow the user credentials that iTunes is running under is different from MetaX. Try this (if you have admin privileges) right click on your iTunes icon and start as admin, then do the same for metax and see if it connects correctly. If so, you're going to have to figure out what user account each of the apps is running in and then make them the same.